Regina High School, located in South Euclid, Ohio, is a National School of Excellence. A college preparatory high school for young women, sponsored by the Sisters of Notre Dame, the high school shares its 50-acre campus with Notre Dame College.

Rich in diversity and strong in unity, Regina is a strong faith community that affirms the rights of every student to develop her academic and creative potential through an education that is thorough, humanizing and Christian. Through a program of academic excellence, Regina empowers young women to be responsible and independent adults by challenging them to think for themselves, develop leadership and be of service to others.

With solid academic programs including pre-engineering, allied health and advanced placement courses, a dedicated religious and lay faculty strives to prepare each student for the challenges and realities of higher education and the workplace. In addition, students may take courses for college credit at Notre Dame College.

Over the past 10 years, 99% of graduates have gone on to attend colleges or universities immediately following graduation.

The school is committed to keeping technology current. To this end, all freshmen receive a laptop computer. The school is completely wireless. Other advancements include the use of SmartBoards, interactive white boards, in every classroom. A comprehensive offering of extracurricular opportunities, including sports, music, drama, social justice and service clubs, enhance the educational experience.